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POPSPharmaceutical Fountain of Youth Could Cost Pennies Five years ago, Sinclair, a Harvard University professor and co-founder of Sirtris Pharmaceuticals, discovered the molecule resveratrol. It targets a gene activated by calorically restricted diets, which have extended the lifespans of laboratory animals from yeast to monkeys.
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POPSWant to Live Forever? Sirtris Pharmaceuticals is testing a fountain-of-youth pill in humans. SRT501 impacts a family of genes in humans and other organisms called "sirtuins," which seem to control a cornucopia of desirable functions in cells that lead to improvements in diseases ranging from obesity and diabetes to Alzheimer's and cancer. Sirtris also is assembling what amounts to a small but burgeoning anti-aging empire as they snap up intellectual property and amass a war chest of cash that includes a $62 million initial share offering last May, added to $103 million raised in private rounds since the company was founded in 2004.
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