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POPSRestoring Damaged Knees Several groups have explored ligament-like scaffolds using collagen fibers, silk, and composites, but with limited success. The ACL replacement developed by Laurencin's team uses a clinically proven, FDA-approved biocompatible polymer, polyL-lactide (PLLA), which is frequently used in drug delivery systems, biomedical devices, bone plates, and sutures. Laurencin's team uses the polymer to stabilize the knee while the scaffold promotes the regeneration of new ligament tissue. The polymer is an absorbable material: its mechanical properties and mass diminish with time and in a manner that permits a favorable biological response.
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