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A new study from researchers at Beth Deaconess Medical Center and Harvard Medical School suggests that tone-deafness may be the result of a missing neural connection. By using a brain imaging technique that allows them to examine the links between the right temporal and frontal lobes, the scientists compared the neural connectivity of 10 tone-deaf subjects against 10 control participants. They found that, in the tone-deaf subjects, there was less connectivity of the arcuate fasciculus (AF), a white matter tract of fiber that serves as a "highway" between the temporal and front brain regions, and is known to be involved in linking language, music and vocal production.

this stretch of fiber was both smaller and less dense in people who are tone-deaf, and that one branch of the neural pathway was in fact undetectable on the scans.
may have similarities to other speech disorders in which there is also an interrupted link between what people hear and what they are able to produce.
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