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clipped from www.nature.com

The man with a hole in his brain

Scans reveal a fluid-filled cavity in the brain of a normal man.

A serious case of water on the brain: scans revealed only a narrow rim of brain material.

Three years ago, a 44-year-old man was admitted to hospital in Marseille, France, complaining of weakness in his left leg. He had no idea what doctors would find to be the source of the problem: a huge pocket of fluid where most of his brain ought to be.
"We were very surprised when we looked for the first time the CT scan," says Lionel Feuillet, a neurologist at the Mediterranean University, Marseille. "The brain was very, very much smaller than normal." Nevertheless, subsequent tests showed the man to have an IQ of 75 — at the lower end of the 'normal range'.
The patient was a married father with two children and a job as a civil servant.
The large black space shows the fluid that replaced much of the patient’s brain (left). For comparison, the images (right) show a typical brain without any abnormalities (Images: Feuillet et al./<I>The Lancet</I>)
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