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clipped from www.fasebj.org
The FASEB Journal. 2006;20:1589-1598.)
TNF receptor superfamily-induced cell death: redox-dependent execution

Here we attempt to review the existing knowledge on the involvement of ROS in death receptor signaling using TNF{alpha}-TNFR1 as the model system, specifically addressing the involvement of intracellular ROS in TNF{alpha}-induced cell death and in TNF{alpha}-induced activation of NF-{kappa}B and JNK and their crosstalk.—Shen, H-M., Pervaiz, S. TNF receptor superfamily-induced cell death: redox-dependent execution.

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