Clipmarks
Sign Up  Install  Learn More  Login 

introducing clip-to-blog

 The easiest way to blog the interesting things you find on the web.
Supports Blogger, Wordpress, Typepad, Live Journal, Movable Type, and Vox.  learn more»
 
 
Post this to your blog
Blog Type:
Blog Username:
Blog Password:
Blog Url:
XML-RPC Url:
Copy and Paste the following code into a new blog post...
Login or Sign Up to save your blog settings.
Title of Post:
Remarks for Post:BBCode  No HTML 
  
 
 
See also:    Email it to friends
Clip Preview:
Cell Signal. 2007 Oct 17
Taxol-induced mitochondrial stress in melanoma cells is mediated by activation of c-Jun N-terminal kinase (JNK) and p38 pathways via uncoupling protein 2
Taxol resulted in the activation of apoptosis signal regulated kinase (ASK)1, c-jun NH(2)-terminal kinase (JNK), p38(MAPK) and extracellular-regulated kinase (ERK) together with the downregulation of uncoupling protein 2 (UCP2)
reactive oxygen species (ROS) were induced and DNA-binding activity of the transcription factors AP-1, ATF-2 and ELK-1 was enhanced
Ultimately, cytochrome c was released, and caspases-9 and -3 as well as PARP were cleaved
Pretreatment of melanoma cells with the JNK inhibitor (SP600125) or the p38 inhibitor (SB203580) blocked taxol-induced UCP2 downregulation, ROS generation and apoptosis, whereas the ERK inhibitor (PD98059) had no such effect
taxol-induced mitochondrial stress occurs through the activation of both JNK and p38 pathways
a novel role for UCP2
 blog it

style options...

Include Clip before or after Remarks  
Customize Clip Colors
Border Background Font
Select Border Color
Select Background Color
Select Font Color
Video Size
If you are clipping video to your blog, and it is too wide, select this option.
Clipmarks Logo and Link
If you chose not to have the Clipmarks logo and link in this blog post, select "Don't include" here.
Line Breaks (Advanced)
If your blog software is configured to automatically convert new lines into HTML, select "Don't format" here to prevent Clipmarks from doing so.
Styles (Advanced)
By default, Clipmarks uses inline styles to format content in your blog post. If you would like to prevent this styling and customize the css rules yourself, select this option and copy this stylesheet into your blog template.