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POPSDo we get wiser with age? "Is age a prerequisite for wisdom, though? We all know a few elderly people who lack wisdom, while we may know few young people that have wisdom in spades. People certainly aren't always at peak brainpower in old age; after all, when wrinkles begin appearing on the face, it usually means that wrinkles have started disappearing on the brain. The brain shrinks slightly with age, and aging leads to a normal decline in cognitive function that may eventually bloom into dementias such as Alzheimer's disease".
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POPSPotential Alzheimer's, Parkinson's Cure Found In Century-old Drug Also impressed is one of Dr. Atamna's co-authors, Bruce Ames, PhD, a senior scientist at Children's and world-renowned expert in nutrition and aging. "What we potentially have is a wonder drug." said Dr. Ames. "To find that such a common and inexpensive drug can be used to increase and prolong the quality of life by treating such serious diseases is truly exciting." Dr. Atamna's research is the first to show that low concentrations of the drug have the ability to slow cellular aging in cultured cells in the laboratory and in live mice. He believes methylene blue has the potential to become another commonplace low-cost treatment like aspirin, prescribed as a blood thinner for people with heart disorders.
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POPSAttacking Alzheimer's with Red Wine and Marijuana "Could people smoke marijuana to prevent Alzheimer's disease if the disease is in the family? We're not saying that, but it might actually work," he said. "What we are saying is it appears that a safe, legal substance that mimics those important properties of marijuana can work on receptors in the brain to prevent memory impairments in aging. So that's really hopeful."
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POPSOlder Brain May Be Wiser “For the young people, it’s as if the distraction never happened,” said an author of the review, Lynn Hasher, a professor of psychology at the University of Toronto and a senior scientist at the Rotman Research Institute. “But for older adults, because they’ve retained all this extra data, they’re now suddenly the better problem solvers. They can transfer the information they’ve soaked up from one situation to another.”
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POPS'Memory pill' could be available soon "The reality is we're not always at our best. After being up at night looking after the kids or travelling, many people would love to have something to sharpen them up. It's not taboo to drink Red Bull. The principle with cognition enhancers is not so different."
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POPSAttacking Alzheimer's with Red Wine and Marijuana What we are saying is it appears that a safe, legal substance the mimics those important properties of marijuana can work What they are saying is, don't grow your own, or legalise pot, but buy their upcoming (probably expensive) cure so the pharmatocracy can keep getting rich. All the while, you'll be protected from this *harmful* weed, via the war on drugs. Win/win, eh? :).
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POPSNew Longevity Drugs Poised to Tackle Diseases of Aging A growing number of scientists suspect that the breakdown of mitochondria is among the most important causes of cell-level changes that eventually cause the body's tissues to degenerate with age. The damage accumulates gradually until hitting some critical mass of malfunction, at which point diseases arrive rapidly. That may be why so many diseases first occur during middle age, and become steadily more common afterwards.
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POPSLethal Egomania & the Glory of Politics Very often activists become so wrapped up in the romance of a cause and seduced by their own image that they forget the issue that they started by advocating, and move into a realm of pure narcissistic idealism. And it is the media, with its voyeuristic bent for sensationalism over reason, that enables many of these well-meaning people to become vacuous soap-box pundits shouting to hear their own voice.
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POPSPalin and the fruit fly or just plain ignorance
One might have thought that Sarah Palin would take a more active interest in one aspect of scientific research. Palin's youngest son has Down's syndrome, a genetic disorder caused by the presence of an extra chromosome 21. Although a geneticist by training, I am certainly no expert on the pathogenesis of this condition, nor the significance of Drosophila research into Down's syndrome. So, I typed "drosophila trisomy 21" into PubMed, the scholarly biomedical equivalent of Google. There were 109 results, the most recent published just the day before Palin's gaffe. The concluding sentence of that study — about the genetic cues that steer nerve fibres around during the growth of the fruit fly — suggests that the paper will "have implications for the pathogenesis of Down's syndrome". These two are drops in the ocean of fruit fly research that have clinical relevance. Down's syndrome, Alzheimer's disease, autism, diabetes, ageing research, cancers of all types
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POPSCup of tea may help boost memory! "Drinking regular cups of tea could help improve your memory, research suggests." Both green tea and black tea inhibit enzymes that help produce protein deposits in the brain which are associated with Alzheimer's disease. Green tea's inhibitive effect lasts longer. Good news for those of us who love to drink tea, particularly green tea. I'm going to brew a pot right now...
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POPSDrug for Longer Life The other drug is a small synthetic chemical that is a thousand times as potent as resveratrol in activating sirtuin and can be given at a much smaller dose. Safety tests in people have just started, with no adverse effects so far. The hope is that activating sirtuins in people would, like a calorically restricted diet in mice, avert degenerative diseases of aging like diabetes, heart disease, cancer and Alzheimer’s. There is no Food and Drug Administration category for longevity drugs, so if the company is to submit a drug for approval, it needs to be for a specific disease. Nonetheless, longevity is what has motivated the researchers and what makes the drugs potentially so appealing.
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