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POPSRight and wrong lessons from biology The opposite view stresses that evolution is an extremely effective way of searching parameter space, and that in consequence is that we should assume that biological design solutions are likely to be close to optimal for the environment for which they’ve evolved. Where these design solutions seem odd from our point of view, their unfamiliarity is to be ascribed to the different ways in which physics works at the nanoscale. At its most extreme, this view regards biological nanotechnology, not just as the existence proof for nanotechnology, but as an upper limit on its capabilities.
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POPSGene silencer and quantum dots reduce protein production to a whisper
Each quantum dot was surrounded by a proton sponge that carried a positive charge. Without any quantum dots attached, the siRNA's negative charge would prevent it from penetrating a cell's wall. With the quantum-dot chaperone, the more weakly charged siRNA complex crosses the cellular wall, escapes from the endosome (a fatty bubble that surrounds incoming material) and accumulates in the cellular fluid, where it can do its work disrupting protein manufacture. Key to the newly published approach is that researchers can adjust the chemical makeup of the quantum dot's proton-sponge coating, allowing the scientists to precisely control how tightly the dots attach to the siRNA. Quantum dots were dramatically better than existing techniques at stopping gene activity. In experiments, a cell's production of a test protein dropped to 2 percent when siRNA was delivered with quantum dots. By contrast, the test protein was produced at 13 percent to 51 percent of normal levels when the siRNA
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POPSVirtual Unreality (Part 1) This speculation about virtual worlds, besides being fun, reflects on the very deep question of Freedom, freedom of the mind, that is. What is freedom? How much freedom can we really take? How are we going to be if and when we become free. Continue to the second part of this clip...
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POPSWhen Unusually Rapid Improvement Becomes Usual Given the existing pressure on such social programs as Social Security and Medicare, I believe one implication of this “unusually rapid improvement” is that these systems will need to be radically overhauled in order to survive this new demographic reality.
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POPSThe Hedonistic Imperative This manifesto outlines a strategy to eradicate suffering in all sentient life. The abolitionist project is ambitious, implausible, but technically feasible. It is defended here on ethical utilitarian grounds. Genetic engineering and nanotechnology allow Homo sapiens to discard the legacy-wetware of our evolutionary past. Our post-human successors will rewrite the vertebrate genome, redesign the global ecosystem, and abolish suffering throughout the living world.
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POPSLife 2.0. A fascinating article of what seems to be near future breakthrough that will radically change the course of human existence. The line between science and science fiction seems to become ever thinner
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