Silent Seizures May Cause Alzheimer's Dementia


	Silent Seizures May Cause Alzheimer's Dementia

BobbyDelray

9-9-2007 9:50 PM

193 views

tags:

alzhiemer's, amyloid-beta, plaque in the brains, dementia, gladstone institute

BobbyDelray says:

I believe this is an important area of research.

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/1927df0a-59a7-4cd3-97d1-4324286e991b/FB16F7F3-6C34-45B1-AF15-72337883356B/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.sciam.com/article.cfm?articleID=DC8B0CA1-E7F2-99DF-3AAE86074DF7591F&chanID=sa007" href="http://www.sciam.com/article.cfm?articleID=DC8B0CA1-E7F2-99DF-3AAE86074DF7591F&chanID=sa007" style="font-size: 11px;">www.sciam.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciam.com/article.cfm?articleID=DC8B0CA1-E7F2-99DF-3AAE86074DF7591F&chanID=sa007"><P>A protein fragment called <A href="http://sciam.com/search/index.cfm?tmpl=proxy&options=0&Q=amyloid&x=0&y=0">amyloid-beta</A> (Aβ) is known to aggregate and create plaque in the brains of Alzheimer's patients. Plaque hinders neuronal activity by gumming up synapses (spaces between cells through which chemical or electrical information is transmitted), eventually damaging nerve cell branches and leading to neuronal death. </P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciam.com/article.cfm?articleID=DC8B0CA1-E7F2-99DF-3AAE86074DF7591F&chanID=sa007"><P>In the current study, a collaborative team of researchers at the Gladstone Institute and the Baylor College of Medicine in Houston, created a strain of mice that overproduces a precursor of Aβ known as amyloid precursor protein. Five to six months after birth, as plaque built up, these animals showed learning and memory deficits illustrated by their difficulty navigating mazes. During autopsies, researchers observed that rewiring had occurred in the late subjects' brains. </P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciam.com/article.cfm?articleID=DC8B0CA1-E7F2-99DF-3AAE86074DF7591F&chanID=sa007"></blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/FB16F7F3-6C34-45B1-AF15-72337883356B/blog/" title="blog or email this clip"><img src="http://content7.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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