Learning How Not To Be Afraid


	Learning How Not To Be Afraid

balthazarus

10-10-2008 10:35 AM

716 views

tags:

fear, neuroscience

balthazarus says:

When Kandel's team used radiation to blunt the birth of new cells in the dentate gyrus, they discovered that their interventions both slowed safety learning and stunted the antidepressant effects of learned safety.

Another study that points to the origin of fear as a biological entity. the glitch is it turning into anxiety.

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/bcb21a9c-e20a-45ae-b35b-9fa1686e34cb/F198DF80-3DE4-4E6E-88A2-1E94759380E2/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.sciencedaily.com/releases/2008/10/081008150445.htm" href="http://www.sciencedaily.com/releases/2008/10/081008150445.htm" style="font-size: 11px;">www.sciencedaily.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciencedaily.com/releases/2008/10/081008150445.htm"><H1>Learning How Not To Be Afraid</H1></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciencedaily.com/releases/2008/10/081008150445.htm">experiments in which they conditioned mice to feel safe in stressful situations</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciencedaily.com/releases/2008/10/081008150445.htm">The behavioral changes observed in the mice squelched anxiety as effectively as 
antidepressant drugs </blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciencedaily.com/releases/2008/10/081008150445.htm">The new study is noteworthy because it reveals in elegant detail how behavioral 
conditioning can affect the brain. </blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciencedaily.com/releases/2008/10/081008150445.htm">Two types of fear, instinctive and learned, have deep evolutionary roots and are 
essential for survival.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciencedaily.com/releases/2008/10/081008150445.htm">But in some people, pathological forms of learned fear can lead to debilitating 
anxiety disorders, post-traumatic stress syndrome, or depression</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciencedaily.com/releases/2008/10/081008150445.htm">"The ability to identify, develop, and exploit conditions of safety and security 
is central to survival and mental health</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciencedaily.com/releases/2008/10/081008150445.htm">taught mice to associate a specific audible tone with protection from an 
impending averse event</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciencedaily.com/releases/2008/10/081008150445.htm">We found that the mice trained for safety could overcome their sense of 
hopelessness in the swim test</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciencedaily.com/releases/2008/10/081008150445.htm">conditioned for safety had a greater number of newborn cells in the dentate 
gyrus</blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/F198DF80-3DE4-4E6E-88A2-1E94759380E2/blog/" title="blog or email this clip"><img src="http://content6.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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