As an example, a well known potent antioxidant, topical alpha-lipoic acid has burst upon the aging skin care scene through it’s popularization by a Yale dermatologist, Dr. Nicholas Perricone. He launched the skin rejuvenation studies of alpha-lipoic and wrote a top selling book extolling it titled The Wrinkle Cure. There seems to be a good foundation for believing skin care products containing Alpha-lipoic Acid are effective and they are considered safe.