Genome engineering goes high speed


	Genome engineering goes high speed

dopesick

8-25-2009 10:54 PM

47 views

tags:

biology, genome, science

dopesick says:

"In a paper published Sunday in Nature, Church and Wang describe how they turned E. coli bacteria into factories for lycopene, an antioxidant that might have anti-cancer properties.

In just three days, they ended up with billions of cells containing various combinations of 24 lycopene-linked genes. Some cells produced five times more lycopene than usual. According to Church, the process would normally take months, even years."
Needless to say how good it is. Just great, great news!

Add a Comment

Login to Comment. Not a member yet? Sign up

Today's Top Clips

visit the Top Clips page

View the Top Clips from August 25, 2009

Embed This Clip In Your Site...

<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/986c6b5b-e241-4076-9ad8-924c797322d8/DB6F1DE9-3A81-4325-9CF2-22676840E13F/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.wired.com/wiredscience/2009/07/cellfactories/" href="http://www.wired.com/wiredscience/2009/07/cellfactories/" style="font-size: 11px;">www.wired.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.wired.com/wiredscience/2009/07/cellfactories/"><H1>Genome Engineering Goes High Speed</H1></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.wired.com/wiredscience/2009/07/cellfactories/"><div align="center"><img src="http://content6.clipmarks.com/blog_cache/www.wired.com/img/6309B5C6-1B55-4AA8-B410-9F680ECD905F" alt="picture-23" /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.wired.com/wiredscience/2009/07/cellfactories/">A new genetic engineering technique could make it as easy to rewrite a genome as it is to read it.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.wired.com/wiredscience/2009/07/cellfactories/"><P>Using the process, which grafts pieces of synthetic DNA into the genomes of dividing cells, researchers generated 15 billion different genomic patterns in just three days. The process would normally take years, and could eventually be used to produce industrial chemicals, drugs, fuel and anything else that comes out of bacteria.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.wired.com/wiredscience/2009/07/cellfactories/"><P>“Automated sequencing really advanced the way we can read genetic information. We hope automated genome engineering will advance the way we write genetic information,” said Harris Wang, a Harvard University biophysicist.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.wired.com/wiredscience/2009/07/cellfactories/"><P>“We are interested in applying this technology to cells that are useful in producing industrially useful chemical, therapeutics and fuels,” from yeast to cyanobacteria, said Wang.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.wired.com/wiredscience/2009/07/cellfactories/"><P>The technique could also be used to design models of diseases — in tissue cultures, or animals — that have large-scale genomic changes.</P></blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/DB6F1DE9-3A81-4325-9CF2-22676840E13F/blog/" title="blog or email this clip"><img src="http://content7.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

New from the makers of Clipmarks: Amplify.com - Don't just share the news...Amplify it!

Clipmarks: Home; New Clips; Top Clips; Dashboard

Popular Topics: News; Life; Science; Technology; Entertainment

Get Started: Sign Up; Install Clipping Tool; How Clipping Works; Clip-to-Blog™; ClipSearch

Tools and Resources: FAQ; ClipWeek; Top Clippers; Top Tags; Site Map

About Clipmarks: About Us; Contact; Copyright; Privacy; EULA

Search Options

Today's Top Clips