Is AIDS an Evolutionary Accident?


	Is AIDS an Evolutionary Accident?

Sheroug

4-2-2008 8:46 AM

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tags:

aids, evolution, accident

1 Comment |

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4-3-2008 12:20 AM

Deepti

I clipped this about Lions getting AIDS sometime back

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/42eebdaf-5691-4dc4-8d4f-4714fe7169cf/D6D1F9F8-29F9-42AC-B965-17F4BF658DDA/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.scientificblogging.com/news_releases/is_aids_an_evolutionary_accident" href="http://www.scientificblogging.com/news_releases/is_aids_an_evolutionary_accident" style="font-size: 11px;">www.scientificblogging.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.scientificblogging.com/news_releases/is_aids_an_evolutionary_accident"><H3><SPAN>Is AIDS An Evolutionary Accident?</SPAN></H3></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.scientificblogging.com/news_releases/is_aids_an_evolutionary_accident">AIDS may partly be the consequence of an evolutionary accident, said Professor 
Frank Kirchhoff from the University of Ulm in Germany</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.scientificblogging.com/news_releases/is_aids_an_evolutionary_accident"><P>“AIDS is a deadly disease in people that is caused by human immunodeficiency virus (HIV). But similar viruses such as simian immunodeficiency virus (SIV), which infects monkeys, usually don’t cause disease in their natural monkey hosts,” says Kirchhoff.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.scientificblogging.com/news_releases/is_aids_an_evolutionary_accident">The researchers found that the Nef protein of most SIVs removes a molecule from 
the cell surface that is critical to make T cells responsive to stimulation.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.scientificblogging.com/news_releases/is_aids_an_evolutionary_accident">Nef proteins in HIV-1 and its closest related SIVs lack this protective function</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.scientificblogging.com/news_releases/is_aids_an_evolutionary_accident">natural SIV infections in monkeys, the ability of the Nef protein to remove a 
specific receptor</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.scientificblogging.com/news_releases/is_aids_an_evolutionary_accident">means that it can still fight off other diseases. Only the Nef proteins of HIV-1 
and its immediate SIV relatives do not perform this function.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.scientificblogging.com/news_releases/is_aids_an_evolutionary_accident">evolutionary loss of a protective function of Nef may contribute to the high 
virulence of HIV-1 in humans” </blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/D6D1F9F8-29F9-42AC-B965-17F4BF658DDA/blog/" title="blog or email this clip"><img src="http://content7.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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