Dimmer Switch for Cancer-Causing Protein


	Dimmer Switch for Cancer-Causing Protein

seaj11

7-12-2008 5:23 PM

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health, medicine, science, cancer, genes

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HealthDay News, 
July 1, 2008
</P><P><DIV>Stanford University <A class="thought" href="javascript:loadBrain('Research')">research</A>ers have found a "dimmer <A class="thought" href="javascript:loadBrain('Switch')">switch</A>" that stops a gene from sending <A class="thought" href="javascript:loadBrain('Protein')">protein</A> signals that promote <A class="thought" href="javascript:loadBrain('Cancer')">cancer</A>.
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When the Myc gene makes too much of the <A class="thought" href="javascript:loadBrain('Protein')">protein</A> Myc, cells lose the ability to kill themselves when they're damaged, and instead keep growing. The <A class="thought" href="javascript:loadBrain('Research')">research</A>ers found that by turning down the Myc <A class="thought" href="javascript:loadBrain('Switch')">switch</A>, they could shrink tumor cells to normal sizes and restore their ability to die.
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Previously, it had been <A class="thought" href="javascript:loadBrain('Thought')">thought</A> that the Myc gene had to be turned off entirely to stop <A class="thought" href="javascript:loadBrain('Cancer')">cancer</A>. <A target="_blank" href="http://www.eurekalert.org/pub_releases/2008-07/sumc-ccr062508.php"> Since low levels of Myc are needed for normal cell functions</A>, Myc couldn't be a target for <A class="thought" href="javascript:loadBrain('Cancer')">cancer</A> treatment. The <A class="thought" href="javascript:loadBrain('Research')">research</A> now means that Myc and similar cellular signals can be a target for therapy.
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Problems with Myc contributed to the <A class="thought" href="javascript:loadBrain('Cancer')">cancer</A>-related deaths of as many as 70,000 Americans each year.</p> <P> </p> <BR /><A target="_new" href="http://www.washingtonpost.com/wp-dyn/content/article/2008/07/01/AR2008070101536.html">Read Original Article&gt;&gt;</A>
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