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Epix Soars 50% On Alzheimer's Data
BobbyDelray
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1
12-19-2007 10:34 PM
302 views
tags:
alzheimer's
,
epix
,
alzheimer’s disease assessment scale
,
brain
1 Comment
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12-29-2007
6:17 AM
tayoulevy
let us hope it is true. let it be a breakthough for 2008
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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/4d6746ef-c5b6-4ed8-a411-84ea2f1dc49e/B41666E5-08A2-4135-880A-FE6A695DF336/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://blogs.forbes.com/sciencebizblog/2007/12/epix-soars-50-o.html" href="http://blogs.forbes.com/sciencebizblog/2007/12/epix-soars-50-o.html" style="font-size: 11px;">blogs.forbes.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://blogs.forbes.com/sciencebizblog/2007/12/epix-soars-50-o.html"><BLOCKQUOTE cite="http://biz.yahoo.com/bw/071218/20071218005206.html?.v=1">EPIX Pharmaceuticals (NASDAQ: <A href="http://finance.yahoo.com/q?s=epix&d=t">EPIX</A> - <A href="http://finance.yahoo.com/q/h?s=epix">News</A>), today announced compelling top-line results from a Phase 2a two-week clinical trial of its novel 5-HT4 agonist, PRX-03140, in patients with Alzheimer<SPAN id="bwanpa3">’</SPAN>s disease. The results show that patients receiving 150 mg of PRX-03140 orally once daily as monotherapy achieved a mean 5.7 point improvement on the Alzheimer<SPAN id="bwanpa4">’</SPAN>s Disease Assessment Scale cognitive subscale (ADAS-cog) versus a 0.2 point worsening in patients on placebo (p= 0.005). Patients on a 50 mg dose of PRX-03140 showed a 1.1 point improvement on the ADAS-cog. </BLOCKQUOTE></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://blogs.forbes.com/sciencebizblog/2007/12/epix-soars-50-o.html"><BLOCKQUOTE cite="http://biz.yahoo.com/bw/071218/20071218005206.html?.v=1">After reviewing these data, Serge Gauthier, M.D., Director of the Alzheimer's Disease Research Unit at McGill University, stated, <SPAN id="bwanpa11">“</SPAN>There is such an urgent and undeniable need for additional safe and effective treatments for Alzheimer<SPAN id="bwanpa12">’</SPAN>s patients. Findings like these data are not only encouraging and compelling <SPAN id="bwanpa13">–</SPAN> they appear to represent a step forward in our ability to understand and combat the effects of Alzheimer<SPAN id="bwanpa14">’</SPAN>s.</BLOCKQUOTE></blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;"> </td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/B41666E5-08A2-4135-880A-FE6A695DF336/blog/" title="blog or email this clip"><img src="http://content8.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>
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