<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/cb2ea28d-9c4e-4228-98ce-5595d68a20da/A9D692C1-8D4D-4361-B8E1-1F3B01FC78F7/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.nlm.nih.gov/medlineplus/news/fullstory_87547.html" href="http://www.nlm.nih.gov/medlineplus/news/fullstory_87547.html" style="font-size: 11px;">www.nlm.nih.gov</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.nlm.nih.gov/medlineplus/news/fullstory_87547.html"><P>The research involved 912 healthy people in Italy, including 60 who had severe osteoarthritis that led to a knee or hip replacement between 1990 and 2005. Those with high levels of vascular cell adhesion molecule 1 (VCAM-1) at the start of the study were most likely to undergo joint replacement, the study found. VCAM-1 is expressed on cells in the cartilage and connective tissue.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.nlm.nih.gov/medlineplus/news/fullstory_87547.html"><P>The study, which appears in the August issue of <I>Arthritis & Rheumatism</I>, is the first to establish a laboratory biomarker for the risk of severe osteoarthritis, according to background information in a news release from the journal. Such biomarkers can lead to early diagnosis of the disease, before clinical symptoms appear. Improved prediction of severe osteoarthritis, experts say, could help identify people who would benefit from interventions such as weight loss, strength training and aerobic exercise.</P></blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/A9D692C1-8D4D-4361-B8E1-1F3B01FC78F7/blog/" title="blog or email this clip"><img src="http://content9.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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