Evolution May Favor Schizophrenia Genes


	Evolution May Favor Schizophrenia Genes

Tommolo

9-7-2007 11:02 AM

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tags:

healt, mind

1 Comment |

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9-18-2007 12:02 PM

neochonetes

Some reputable anthropologists believe that shamans and other "holy people" may have some schizophrenic tendencies. While others may use ritualized drugs to reach this state in which they hear voices and have other temporarily induced symptoms of schizophrenia related to their religious duties.

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/e95a2f5e-6814-4e94-bd16-0cf5ee280c1c/A2831CA4-DA31-4655-A434-A495C3ACCC80/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.sciam.com/article.cfm?chanId=sa003&articleId=DC9F2509-E7F2-99DF-3621E37563E14B7B" href="http://www.sciam.com/article.cfm?chanId=sa003&articleId=DC9F2509-E7F2-99DF-3621E37563E14B7B" style="font-size: 11px;">www.sciam.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciam.com/article.cfm?chanId=sa003&articleId=DC9F2509-E7F2-99DF-3621E37563E14B7B"><A href="http://sciam.com/search/index.cfm?i=1&options=0&q=schizophrenia&tmpl=proxy&u1=q&x=0&y=0" linkindex="69" set="yes">Schizophrenia</A>, the psychotic disorder marked by hallucinations, multiple personalities and cognitive disorganization, affects roughly 1 percent of the U.S. population. Many of those afflicted, however, also have reduced reproductive fitness, which means they are less likely to pass a genetic profile associated with the condition onto their offspring</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciam.com/article.cfm?chanId=sa003&articleId=DC9F2509-E7F2-99DF-3621E37563E14B7B">researchers reached a striking conclusion that several gene variants linked to schizophrenia were actually <I>positively</I> selected and remained largely unchanged over time, suggesting that there was some advantage to having them</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciam.com/article.cfm?chanId=sa003&articleId=DC9F2509-E7F2-99DF-3621E37563E14B7B">Over the past decade, several dozen genes have been identified as potential culprits, and scientists believe that several genes cause disruptions in protein formations predisposing a person to schizophrenia</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciam.com/article.cfm?chanId=sa003&articleId=DC9F2509-E7F2-99DF-3621E37563E14B7B"> 28 of the schizophrenia-associated genes have been evolutionarily preferred in recent years by either Caucasian, Asian or African populations</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sciam.com/article.cfm?chanId=sa003&articleId=DC9F2509-E7F2-99DF-3621E37563E14B7B">we don't really know what the basis of the selection has been</blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/A2831CA4-DA31-4655-A434-A495C3ACCC80/blog/" title="blog or email this clip"><img src="http://content7.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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