Scientists Discover Molecules That Reverse Cirrhosis (Edited by Cliff Eastham)


	Scientists Discover Molecules That Reverse Cirrhosis (Edited by Cliff Eastham)

Skipper61

4-1-2008 11:42 AM

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/42274843-3bc3-44c6-a7f5-690fe7764668/9FB839A1-0E9B-4E50-B37E-DC1104C05281/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.redorbit.com/news/health/1319884/scientists_discover_molecules_that_reverse_liver_cirrhosis/index.html" href="http://www.redorbit.com/news/health/1319884/scientists_discover_molecules_that_reverse_liver_cirrhosis/index.html" style="font-size: 11px;">www.redorbit.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.redorbit.com/news/health/1319884/scientists_discover_molecules_that_reverse_liver_cirrhosis/index.html"><div align="center"><img src="http://content7.clipmarks.com/blog_cache/www.redorbit.com/img/F6F33AE6-7190-4AB6-A23C-0BED02B1DED6" alt="" /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.redorbit.com/news/health/1319884/scientists_discover_molecules_that_reverse_liver_cirrhosis/index.html"><DIV>
	Japanese scientists have designed artificial molecules that reversed liver cirrhosis in rats.</DIV></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.redorbit.com/news/health/1319884/scientists_discover_molecules_that_reverse_liver_cirrhosis/index.html"><DIV>Cirrhosis is a hardening or scarring of the liver that occurs when liver cells begin producing collagen, a fibrous material found in skin and tendons.  </DIV></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.redorbit.com/news/health/1319884/scientists_discover_molecules_that_reverse_liver_cirrhosis/index.html"><DIV>The researchers said they designed molecules that block collagen production by the liver’s "stellate cells," which are also known to absorb vitamin A.  The scientists loaded these molecules into vitamin-A coated carriers, which tricked the stellate cells into absorbing the molecules.</DIV></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.redorbit.com/news/health/1319884/scientists_discover_molecules_that_reverse_liver_cirrhosis/index.html"><DIV>"By packaging the (molecules) in carriers coated with vitamin A, they tricked the stellate cells into letting in the inhibitor, which shut down collagen secretion," the researchers wrote in a report about their work.</DIV></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.redorbit.com/news/health/1319884/scientists_discover_molecules_that_reverse_liver_cirrhosis/index.html"><DIV>During the study, the researchers injected the vitamin A-laced molecules in rats with induced liver cirrhosis.</DIV></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.redorbit.com/news/health/1319884/scientists_discover_molecules_that_reverse_liver_cirrhosis/index.html">"We were able to completely eradicate the fibrosis by injecting this agent ..
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. we cured them of the cirrhosis," said Yoshiro Niitsu</blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/9FB839A1-0E9B-4E50-B37E-DC1104C05281/blog/" title="blog or email this clip"><img src="http://content8.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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