Zip memories don't return

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	Zip memories don't return

cresvumom

11-14-2009 2:08 PM

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/ac5b9df1-1363-44ba-801a-ece7cc7052ad/96D85A81-C2F2-4E13-945A-DA7AF7F6BA3C/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://consults.blogs.nytimes.com/2009/04/13/memory-erasing/" href="http://consults.blogs.nytimes.com/2009/04/13/memory-erasing/" style="font-size: 11px;">consults.blogs.nytimes.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://consults.blogs.nytimes.com/2009/04/13/memory-erasing/"><P>We, as well as other researchers, have done extensive experiments to try to see if, once disrupted by ZIP, a memory ever comes back. We waited weeks, we gave reminders, but the memory never seemed to return. Remarkably, giving the drug right before or even during the training had no effect on long-term memory formation tested a few days later. The drug has a pure “retrograde” effect. That’s why it’s so different from clinical cases of amnesia due to brain injuries or dementias like Alzheimer’s, which affect both formation of new memories and recall of old. Our experimental result also suggests that the PKMzeta is not made immediately during learning, but after a few hours, and that the drug itself only lasts a few hours.</P></blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/96D85A81-C2F2-4E13-945A-DA7AF7F6BA3C/blog/" title="blog or email this clip"><img src="http://content8.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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