Silk the key to rebuilding bone


	Silk the key to rebuilding bone

pokkets

12-15-2008 8:50 PM

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/90914c0d-922e-4e76-9a88-ec93bd899c66/9151A9B8-B620-4E8D-8669-BF60C280E1DD/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.abc.net.au/science/articles/2008/11/18/2422636.htm?site=science&topic=latest" href="http://www.abc.net.au/science/articles/2008/11/18/2422636.htm?site=science&topic=latest" style="font-size: 11px;">www.abc.net.au</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/11/18/2422636.htm?site=science&topic=latest">Bianca Nogrady</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/11/18/2422636.htm?site=science&topic=latest"><P class="first">Silkworms and spiders could hold the key to engineering healthy bone tissue to replace damaged bone and teeth, according to a US biomedical engineer.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/11/18/2422636.htm?site=science&topic=latest"><div align="center"><img src="http://content6.clipmarks.com/blog_cache/www.abc.net.au/img/E24FF03B-1CCE-4281-8B8C-A4FF7F179D43" alt="missing tooth" /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/11/18/2422636.htm?site=science&topic=latest"><P>Speaking at the <A target="_blank" href="http://www.ahmrcongress.org.au/">Australian Health and Medical Research Congress</A> in Brisbane, Professor David Kaplan from <A target="_blank" href="http://www.tufts.edu/">Tufts University</A> in Massachusetts says spider and silkworm silks are among the strongest natural fibres in existence, and have incredible properties.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/11/18/2422636.htm?site=science&topic=latest"><P>"When you look at the mechanical properties of single fibre silks, they are remarkable in terms of tension and compression," says Kaplan.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/11/18/2422636.htm?site=science&topic=latest"><P>Silk has the added advantage of being bio-compatible, so it can be used in humans. He says it has already been approved by the US Food and Drug Administration for use in early human clinical trials. </P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/11/18/2422636.htm?site=science&topic=latest">"We have learned how to make some pretty nice bone using silk as versatile protein-based matrix,</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/11/18/2422636.htm?site=science&topic=latest">This matrix is normally made in body from hydroxyapatite and collagen, which is then populated by specialised cells that build and remodel the bone</blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/9151A9B8-B620-4E8D-8669-BF60C280E1DD/blog/" title="blog or email this clip"><img src="http://content7.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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