Cocaine Vaccine in the Works


	Cocaine Vaccine in the Works

CarnivalBorn

1-2-2008 11:12 PM

268 views

tags:

drugs, cocaine, fda

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/e34384a6-cf80-4393-84cf-147622aa7a32/78BAC2FF-5743-4311-9A2C-A7C75F5DB203/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://dsc.discovery.com/news/2008/01/02/cocaine-vaccine.html?dcitc=w19-502-ak-0000" href="http://dsc.discovery.com/news/2008/01/02/cocaine-vaccine.html?dcitc=w19-502-ak-0000" style="font-size: 11px;">dsc.discovery.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://dsc.discovery.com/news/2008/01/02/cocaine-vaccine.html?dcitc=w19-502-ak-0000">Two Baylor College of Medicine researchers in Houston are working on a cocaine vaccine</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://dsc.discovery.com/news/2008/01/02/cocaine-vaccine.html?dcitc=w19-502-ak-0000">Dr. Tom Kosten, a psychiatry professor who is being assisted in the research by his wife, Therese, a psychologist and neuroscientist</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://dsc.discovery.com/news/2008/01/02/cocaine-vaccine.html?dcitc=w19-502-ak-0000">"At some point, most users will give in to temptation and relapse, but those for whom the vaccine is effective won't get high and will lose interest."</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://dsc.discovery.com/news/2008/01/02/cocaine-vaccine.html?dcitc=w19-502-ak-0000">The vaccine, currently in clinical trials, stimulates the immune system to attack the real thing when it's taken</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://dsc.discovery.com/news/2008/01/02/cocaine-vaccine.html?dcitc=w19-502-ak-0000">The immune system -- unable to recognize cocaine and other drug molecules because they are so small -- can't make antibodies to attack them</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://dsc.discovery.com/news/2008/01/02/cocaine-vaccine.html?dcitc=w19-502-ak-0000">To help the immune system distinguish the drug, Kosten attached inactivated cocaine to the outside of inactivated cholera proteins</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://dsc.discovery.com/news/2008/01/02/cocaine-vaccine.html?dcitc=w19-502-ak-0000">In response, the immune system not only makes antibodies to the combination, which is harmless, but also recognizes the potent naked drug when it's ingested. The antibodies bind to the cocaine and prevent it from reaching the brain</blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/78BAC2FF-5743-4311-9A2C-A7C75F5DB203/blog/" title="blog or email this clip"><img src="http://content7.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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