DNA Sudoku | Clipmarks


	DNA Sudoku

Mohir

7-4-2009 8:31 AM

265 views

tags:

dna, mathematics

Mohir says:

more at source

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/35e71e07-f4ab-46b8-a7c2-c009e108faa4/7471ABE6-FD56-403A-88A3-1B7522714F0C/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.scientificamerican.com/article.cfm?id=dna-sudoku" href="http://www.scientificamerican.com/article.cfm?id=dna-sudoku" style="font-size: 11px;">www.scientificamerican.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.scientificamerican.com/article.cfm?id=dna-sudoku"><H2>Researchers get help from a venerable number theory and a popular puzzle game to solve genetic medical mysteries</H2></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.scientificamerican.com/article.cfm?id=dna-sudoku"><div align="center"><img src="http://content6.clipmarks.com/blog_cache/www.scientificamerican.com/img/ADA59D0C-7ADD-4ECA-A9D6-9F85741D3E2A" alt="" /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.scientificamerican.com/article.cfm?id=dna-sudoku"><DIV>A 2,000-year-old math theorem, along with <A href="http://www.scientificamerican.com/article.cfm?id=the-science-behind-sudoku" linkindex="60">Sudoku</A>, may soon help researchers untangle DNA at blazing speeds.</DIV></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.scientificamerican.com/article.cfm?id=dna-sudoku">Hunting for a particular genetic mutation in hundreds of thousands of specimens can be an expensive and time-consuming process. In the past several years, faster <A href="http://www.scientificamerican.com/article.cfm?id=multiplexing" linkindex="61">multiplex DNA sequencing machines</A> have sped up the acquisition of data, but researchers have still been hobbled by having to label each sample with a unique molecular identifier (or bar code) for analysis.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.scientificamerican.com/article.cfm?id=dna-sudoku">Scientists</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.scientificamerican.com/article.cfm?id=dna-sudoku"> are proposing a new take on a very old idea to tackle large data sets simultaneously. <A href="http://hannonlab.cshl.edu/dna_sudoku/main.html" linkindex="62">The team</A> is applying the Chinese remainder theorem to pinpoint single samples in larger pools, which are arranged in rows and columns.</blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/7471ABE6-FD56-403A-88A3-1B7522714F0C/blog/" title="blog or email this clip"><img src="http://content7.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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