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Paraplegic rats trained to run again
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9-21-2009 7:34 AM
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health
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9-21-2009
7:52 AM
The Infowarrior
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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/ff1c0cbb-7377-4f8b-8fa5-7de91058804d/65854B68-C91E-4036-BF91-B768B2C0289C/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.abc.net.au/news/stories/2009/09/21/2691423.htm" href="http://www.abc.net.au/news/stories/2009/09/21/2691423.htm" style="font-size: 11px;">www.abc.net.au</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/news/stories/2009/09/21/2691423.htm"><P class="first">Researchers in Switzerland have been able to make paralysed rats run again, using a treatment that could eventually help humans with spinal cord injuries.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/news/stories/2009/09/21/2691423.htm"><P>The new study shows paraplegic rats do not need their severed nerve fibres to be regenerated or repaired to regain motion.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/news/stories/2009/09/21/2691423.htm"><P>Gregoire Courtine, professor of neurobiology at the University of Zurich, says instead a combination of drugs, electricity and regular exercise can do the trick.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/news/stories/2009/09/21/2691423.htm">"We used a combination of electrical stimulation, [a] different site on the docile aspect of the spinal cord, and adjusting drugs to transform the circuits from a non-functional state to a highly functional state</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/news/stories/2009/09/21/2691423.htm">Indeed, after we did the stimulation, 10 minutes later the animal is able to walk and to stand on the treadmill continuously</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/news/stories/2009/09/21/2691423.htm">The rats could not initiate the motion, but they were not just reacting to the treadmill</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/news/stories/2009/09/21/2691423.htm">Once the limbs had been reanimated, the scientists then trained the rats for two months, changing the speed and direction of the treadmills</blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;"> </td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/65854B68-C91E-4036-BF91-B768B2C0289C/blog/" title="blog or email this clip"><img src="http://content6.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>
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