The Genetics of Depression


	The Genetics of Depression

Moonowler

7-11-2007 2:06 AM

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/97d9d21a-237b-4806-8d09-a053fdb9e537/6354BD29-2000-4C1C-B941-97BE0ADCC98F/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.technologyreview.com/read_article.aspx?ch=specialsections&sc=genomics&id=18531" href="http://www.technologyreview.com/read_article.aspx?ch=specialsections&sc=genomics&id=18531" style="font-size: 11px;">www.technologyreview.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.technologyreview.com/read_article.aspx?ch=specialsections&sc=genomics&id=18531">In the past few years, complex genetic diseases such as Alzheimer's and diabetes have slowly yielded their genetic secrets. But depression and bipolar disorder, two mood disorders that take a massive toll on public health worldwide, have yet to succumb to genetic analysis.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.technologyreview.com/read_article.aspx?ch=specialsections&sc=genomics&id=18531">"We've seen some evidence that those kinds of things are possible in some other conditions, like Alzheimer's disease or obesity, which were not well understood until genetic findings began to reveal unexpected genetic pathways."</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.technologyreview.com/read_article.aspx?ch=specialsections&sc=genomics&id=18531">Uncovering the genetic variations underlying these disorders could help. But mood disorders are likely caused by many different genetic variations, each contributing a relatively small effect. "To find genes associated with macular degeneration, it took about 500 patients, Crohn's disease, 1,500 patients, type 2 diabetes, about 10,000 patients,"</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.technologyreview.com/read_article.aspx?ch=specialsections&sc=genomics&id=18531">Two large-scale, multicenter trials could bring the first wave of answers. </blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/6354BD29-2000-4C1C-B941-97BE0ADCC98F/blog/" title="blog or email this clip"><img src="http://content9.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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