New source of heart stem cells discovered


	New source of heart stem cells discovered

Silkweaver

6-22-2008 8:39 PM

727 views

tags:

medicine, stem cell therapy

Silkweaver says:

This could eventually heal some broken hearts...

1 Comment |

Add a Comment

6-26-2008 7:47 AM

wiganfootie

Very interesting

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/9b77b464-8496-42c5-916b-27ce6c3e3e8b/5D22BDB6-9770-4F9D-A779-1474672C0A34/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.physorg.com/news133364595.html" href="http://www.physorg.com/news133364595.html" style="font-size: 11px;">www.physorg.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.physorg.com/news133364595.html"><div align="center"><img src="http://content8.clipmarks.com/blog_cache/www.physorg.com/img/F91250C6-66F6-4E03-8822-9C37A336298E" alt="Pu and Zhou tagged the Wt-1 expressing epicardial cells with a fluorescent red protein then allowed the cells to differentiate. The image shows a descendent cardiomyocyte (green) that carries the same red marker and another cell that arose from diffe ..." /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.physorg.com/news133364595.html">Researchers at Children's Hospital Boston are continuing to document the heart's earliest origins.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.physorg.com/news133364595.html">Now, they have pinpointed a new, previously unrecognized group of stem cells that give rise to cardiomyocytes, or heart muscle cells.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.physorg.com/news133364595.html">These stem cells, located in the surface of the heart, or epicardium, advance the hope of being able to regenerate injured heart tissue.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.physorg.com/news133364595.html">This finding, published online by the journal <I>Nature</I> on June 22, comes on the heels of parallel cardiac stem cell discoveries in 2006, at both Children's and Massachusetts General Hospital.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.physorg.com/news133364595.html">"If you're going to regenerate a tissue, you need to regenerate the whole tissue, not just the cardiomyocytes," said Pu. "This progenitor population contains all the potential to regenerate multiple tissue types within the heart."
</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.physorg.com/news133364595.html">whether this newly-discovered progenitor is truly multipotent</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.physorg.com/news133364595.html">how multipotency is controlled, and whether this can be used therapeutically to benefit adults with heart failure.
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