Navigation from the toolbar
The address bar shortcut should be as instinctual as breathing by now, but there's a few more shortcuts to that top bar that you should keep in mind
* Select location bar: Ctrl/Cmd+L or Alt+D
* Select search bar: Ctrl/Cmd+K
* Back: Backspace or Alt/Cmd+Left
* Forward: Alt/Option+Right or Shift+Backspace
* Change search engine: Ctrl/Cmd+Down (Next) +Up (Previous)

The last shortcut, used to change the search engine

A less-known feature, Caret browsing, inserts a cursor into the text of the page and is very useful for highlighting and copying text.

I'm constantly using cmd/ctrl-T to open a new tab and cmd/ctrl-shift-T to reopen the last closed tab when I close one by mistake.

Cmd-W to close the current tab also comes in handy.

cmd/ctrl-shift-T

Good tip, ericskiff, thank,you

you're welcome, oh, in case your use gmail, you can press cmd/shift-? and the shortcut menu will pop up. I use it a lot