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Dual action Alzheimers's drug hope
Tri-City Psychology
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6-12-2008 2:32 PM
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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/6aff9e9e-0fd9-4fd9-9b1f-33a6d81d4bb7/52FED4F3-8E1A-4688-B7F0-2D14D4E485CD/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://news.bbc.co.uk/2/hi/health/7447680.stm" href="http://news.bbc.co.uk/2/hi/health/7447680.stm" style="font-size: 11px;">news.bbc.co.uk</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://news.bbc.co.uk/2/hi/health/7447680.stm"><B>Experimental drugs are being hailed as a potentially exciting step forward in the treatment of Alzheimer's.</B></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://news.bbc.co.uk/2/hi/health/7447680.stm"><div align="center"><img src="http://content9.clipmarks.com/blog_cache/news.bbc.co.uk/img/2B4E1FEA-1163-4907-949E-D26AB9058A5D" alt="Alzheimer's cell" /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://news.bbc.co.uk/2/hi/health/7447680.stm"><P>The drugs, still in clinical trials, form a new class called gamma-secretase modulators (GSM). </P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://news.bbc.co.uk/2/hi/health/7447680.stm"><P>A study in Nature shows they cut levels of the protein that forms the sticky clumps associated with Alzheimer's. </P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://news.bbc.co.uk/2/hi/health/7447680.stm"><P>In addition, the international research team found the drugs boost levels of shorter pieces of the same protein which help to inhibit clump formation. </P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://news.bbc.co.uk/2/hi/health/7447680.stm"><table background="" bgcolor=""><tr><TD><DIV><DIV><IMG height="20" hspace="0" src="http://newsimg.bbc.co.uk/nol/shared/img/v3/start_quote_rb.gif" width="34" vspace="0" border="0" /> <B>This is an exciting step forward towards a potential new treatment for Alzheimer's disease</B> <IMG height="20" hspace="0" src="http://newsimg.bbc.co.uk/nol/shared/img/v3/end_quote_rb.gif" width="33" align="right" vspace="0" border="0" /><BR clear="all" /></DIV></DIV><DIV><DIV>Rebecca Wood<BR />Alzheimer's Research Trust</DIV></DIV></TD></tr></table></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://news.bbc.co.uk/2/hi/health/7447680.stm"><P>The researchers found that GSMs stick to amyloid beta protein that is already in the brain, preventing it from sticking together. </P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://news.bbc.co.uk/2/hi/health/7447680.stm"><P>Researcher Dr Todd Golde, a neuroscientist at the Mayo Clinic in Jacksonville, said: "This broadens the notion of what drugs can do and therefore has wide-reaching implication for future drug discovery for many different disorders." </P></blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;"> </td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/52FED4F3-8E1A-4688-B7F0-2D14D4E485CD/blog/" title="blog or email this clip"><img src="http://content6.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>
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