<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/dddf325f-4da4-4c09-939d-493c9caf9922/4F495123-B8C8-4C05-8D3A-386B56EB787C/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.nytimes.com/2009/10/27/science/27rat.html?_r=1&th&emc=th#" href="http://www.nytimes.com/2009/10/27/science/27rat.html?_r=1&th&emc=th#" style="font-size: 11px;">www.nytimes.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.nytimes.com/2009/10/27/science/27rat.html?_r=1&th&emc=th#"><div align="center"><img src="http://content8.clipmarks.com/blog_cache/www.nytimes.com/img/8CD83BE0-5051-4E4B-A464-4C565B5E4DE9" alt="" /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.nytimes.com/2009/10/27/science/27rat.html?_r=1&th&emc=th#">Mice are very prone to <A title="In-depth reference and news articles about Cancer." href="http://health.nytimes.com/health/guides/disease/cancer/overview.html?inline=nyt-classifier">cancer</A>; in some strains, 90 percent of them die of <A title="In-depth reference and news articles about Tumor." href="http://health.nytimes.com/health/guides/disease/tumor/overview.html?inline=nyt-classifier">tumors</A>. People have stronger defenses against cancer, as is necessary for a long-lived animal: the disease accounts for 23 percent of human mortality. But the mole rat has taken its anticancer defenses even further: it seems not to get the disease at all.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.nytimes.com/2009/10/27/science/27rat.html?_r=1&th&emc=th#"><P>Dr. Gorbunova, who works at the <A title="More articles about the University of Rochester." href="http://topics.nytimes.com/top/reference/timestopics/organizations/u/university_of_rochester/index.html?inline=nyt-org">University of Rochester</A>, has taken a first step toward understanding the genetic basis of the mole rat’s surprising <A title="In-depth reference and news articles about Immune response." href="http://health.nytimes.com/health/guides/specialtopic/immune-response/overview.html?inline=nyt-classifier">immunity</A> to cancer. She and her colleagues have found that the rats’ cells have a double system for inhibiting irregular proliferation, compared with the single system in human cells.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.nytimes.com/2009/10/27/science/27rat.html?_r=1&th&emc=th#"> The mole rat’s double system may be part of the reason for its remarkable immunity to cancer.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.nytimes.com/2009/10/27/science/27rat.html?_r=1&th&emc=th#"><P>But Ronald da Pinho of Harvard Medical School, an expert on cancer and telomeres, disagreed, saying that inactive telomerase can be a cancer risk for human cells because it leads to genetic instability.</P></blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/4F495123-B8C8-4C05-8D3A-386B56EB787C/blog/" title="blog or email this clip"><img src="http://content9.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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