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'Elixir of youth' drug could fight HIV and ageing
Silkweaver
follow
23
11-16-2008 8:34 PM
461 views
tags:
hiv
,
telomerase
,
life extension
,
immune system
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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/99865987-36ae-44df-95d9-bc9adec8dcc4/364249C6-6EB3-425D-B120-FF360984D26F/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.newscientist.com/article/dn16035" href="http://www.newscientist.com/article/dn16035" style="font-size: 11px;">www.newscientist.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.newscientist.com/article/dn16035"><div align="center"><img src="http://content6.clipmarks.com/blog_cache/www.newscientist.com/img/83FB215D-0D51-45B2-8EA8-5368416C647D" alt="Electron microscopic image of a single human " /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.newscientist.com/article/dn16035"><P>A drug extracted from a plant used in Chinese medicine has helped immune cells fight HIV and raises the possibility of slowing the ageing process in other parts of our bodies.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.newscientist.com/article/dn16035"><P>The method hinges upon <A href="http://www.newscientist.com/article/mg18224421.400-chromosome-clock-ticks-out-our-fate.html" linkindex="31">telomeres</A> - caps of repetitive DNA found at the ends of chromosomes. These get shorter as cells age and are thought to affect the cell's lifespan.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.newscientist.com/article/dn16035"><P>The caps can be rebuilt with an enzyme called telomerase, and some people have suggested it might be possible to <A href="http://www.newscientist.com/article/dn3337-shorter-telomeres-mean-shorter-life.html" linkindex="32" set="yes">extend human life by boosting telomerase production</A> - though this has never been tested.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.newscientist.com/article/dn16035"><P>Now <A target="ns" href="http://portal.ctrl.ucla.edu/pathology/institution/personnel?personnel_id=45371" linkindex="33">Rita Effros</A> at the University of California in Los Angeles has used a drug that boosts telomerase to enhance the immune response to viruses.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.newscientist.com/article/dn16035">It is beginning to look like telomerase is doing more than just keeping telomeres from getting too short," says Effros. "It seems to be mediating some anti-viral mechanisms as well</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.newscientist.com/article/dn16035">Aubrey de Grey of the <A target="ns" href="http://www.methuselahfoundation.org/" linkindex="36" set="yes">Methuselah Foundation</A>, which promotes research into lifespan extension, says the study is a big step forward</blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;"> </td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/364249C6-6EB3-425D-B120-FF360984D26F/blog/" title="blog or email this clip"><img src="http://content7.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>
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