Higher Risk in AIDS vaccine study


	Higher Risk in AIDS vaccine study

shancypants

11-14-2007 8:49 AM

200 views

tags:

hiv/aids, aids, vaccine, merck

shancypants says:

I don't understand if it is because those who were given the vaccine happened to engage in more high risk activities- or if the vaccine actually deposited, as vaccines do, enough of HIV to infect people with AIDS. This could be a disaster for Merck and co.

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/802416a1-4520-4387-94c9-aa1353aa8263/355246A5-DEEB-4C79-B56B-241FF78FB27C/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.sfgate.com/cgi-bin/article.cgi?f=/c/a/2007/11/14/MNSOTBQ2D.DTL" href="http://www.sfgate.com/cgi-bin/article.cgi?f=/c/a/2007/11/14/MNSOTBQ2D.DTL" style="font-size: 11px;">www.sfgate.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sfgate.com/cgi-bin/article.cgi?f=/c/a/2007/11/14/MNSOTBQ2D.DTL"><H1>People in AIDS vaccine study to be warned of possible higher risk</H1></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sfgate.com/cgi-bin/article.cgi?f=/c/a/2007/11/14/MNSOTBQ2D.DTL"><P><STRONG>(11-13) 17:53 PST SAN FRANCISCO</STRONG> --
Nearly 3,000 volunteers who participated in a study of an experimental AIDS vaccine that may have unexpectedly raised the risk of contracting HIV will be notified shortly whether they received the actual vaccine or a placebo.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sfgate.com/cgi-bin/article.cgi?f=/c/a/2007/11/14/MNSOTBQ2D.DTL"><P>Although the study showed definitively that the vaccine did not protect against HIV infection, the early trend showing increased risk among the vaccinated was not proven. So far, 49 of the 1,500 volunteers who received the vaccine have become infected, compared with 33 among a similarly sized group given a placebo. </P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.sfgate.com/cgi-bin/article.cgi?f=/c/a/2007/11/14/MNSOTBQ2D.DTL"><P> The alternative would have been to allow any participants to be told whether they received the vaccine if they asked to know, but many researchers concluded that there would be little extra information gained by this strategy of "voluntary un-blinding."</P></blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/355246A5-DEEB-4C79-B56B-241FF78FB27C/blog/" title="blog or email this clip"><img src="http://content8.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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