<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/3dc90915-6887-40e8-bdbe-e8ed06220e41/2EE57B15-2A56-4712-9F51-797894349754/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.nsf.gov/news/news_summ.jsp?cntn_id=114598&org=NSF&from=news" href="http://www.nsf.gov/news/news_summ.jsp?cntn_id=114598&org=NSF&from=news" style="font-size: 11px;">www.nsf.gov</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.nsf.gov/news/news_summ.jsp?cntn_id=114598&org=NSF&from=news"><div align="center"><img src="http://content8.clipmarks.com/blog_cache/www.nsf.gov/img/788CB459-3A60-4326-8A1C-204FFAB5968A" alt="Cartoon diagram of an enzyme." /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.nsf.gov/news/news_summ.jsp?cntn_id=114598&org=NSF&from=news"><P>Cartoon diagram of an enzyme, an example of the class of FDTS enzymes. <A href="http://www.nsf.gov/news/news_images.jsp?cntn_id=114598&org=NSF">Credit and Larger Version</A></P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.nsf.gov/news/news_summ.jsp?cntn_id=114598&org=NSF&from=news"><P>The chemical reaction discovered by the researchers uses an enzyme called flavin-dependent thymidylate synthase, or FDTS. The enzyme is coded by the <EM>thyX</EM> gene and has been found primarily in bacteria and viruses, including several human pathogens and biological warfare agents. In the future, scientists may use this knowledge for the development of new antibacterial and antiviral drugs.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.nsf.gov/news/news_summ.jsp?cntn_id=114598&org=NSF&from=news"><P><STRONG>Related Websites<BR /></STRONG>Nature Letter: An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene: <A href="http://www.nsf.gov/news/longurl.cfm?id=154">/news/longurl.cfm?id=154</A><BR />Nature News and Views: Biochemistry: Anchors Away: <A href="http://www.nsf.gov/news/longurl.cfm?id=155">/news/longurl.cfm?id=155</A><BR />University of Iowa News Release: UI chemists' DNA biosynthesis discovery could lead to better antibiotics: <A href="http://www.nsf.gov/news/longurl.cfm?id=156">/news/longurl.cfm?id=156</A><BR /></P></blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/2EE57B15-2A56-4712-9F51-797894349754/blog/" title="blog or email this clip"><img src="http://content9.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>

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