Cancer-fighting gene also delays ageing


	Cancer-fighting gene also delays ageing

Deepti

7-19-2007 5:43 AM

416 views

tags:

study, research, cancer, gene, aging, science, lifespan

3 Comments |

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7-19-2007 6:59 AM

medisland

That's really something!.. P53 gene has always been known to stimulate our cells death process (thus believed to cause aging).
While the opposite gene, Bcl2 is the one known to inhibit the process & hence was expected to be 'the fountain of youth'. Cool!.

7-19-2007 9:57 AM

monalisa

Wrong wrong wrong, i'll take results based on a few rats with a pinch of salt to swallow

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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/1d8dc768-a9e2-49f9-b4d6-67b0a42694af/2C614083-990A-48BD-98C8-523A3A3CA18E/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.reuters.com/article/scienceNews/idUSL1888172120070718" href="http://www.reuters.com/article/scienceNews/idUSL1888172120070718" style="font-size: 11px;">www.reuters.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.reuters.com/article/scienceNews/idUSL1888172120070718">One of the genes that protects us from cancer may also help delay ageing, according to a new study published on Wednesday</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.reuters.com/article/scienceNews/idUSL1888172120070718">researchers genetically engineered mice to have an extra copy of a key cancer-fighting gene called p53 and found it also played an important role in delaying ageing.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.reuters.com/article/scienceNews/idUSL1888172120070718">Previous cancer studies have shown that p53 can actually cause premature ageing symptoms by killing too many cells when it goes into overdrive, but Serrano said his research strictly regulated the gene so that it turned on only when needed</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.reuters.com/article/scienceNews/idUSL1888172120070718">The mice lived 16 percent longer in their average lifespan</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.reuters.com/article/scienceNews/idUSL1888172120070718">The p53 gene, when working properly, makes sure that damaged cells destroy themselves and do not divide uncontrollably to cause tumors. If the gene is mutated or inactivated the control mechanism does not work</blockquote><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content9.clipmarks.com/images/clip-icon.gif" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.reuters.com/article/scienceNews/idUSL1888172120070718?pageNumber=2" href="http://www.reuters.com/article/scienceNews/idUSL1888172120070718?pageNumber=2" style="font-size: 11px;">www.reuters.com</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.reuters.com/article/scienceNews/idUSL1888172120070718?pageNumber=2">research has shown that mice and worms that eat less have slower metabolisms and live longer</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.reuters.com/article/scienceNews/idUSL1888172120070718?pageNumber=2">his study offers evidence that the mice can benefit from the extra copy of the genes without having to be starved</blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;">&nbsp;</td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/2C614083-990A-48BD-98C8-523A3A3CA18E/blog/" title="blog or email this clip"><img src="http://content6.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>