I have lived with depression since I was about 6 years old. I found myself wary about depression medications as they became popular, thinking, these things are altering you BRAIN, for God's sake, these are chemicals with effects on the tissues that have you apprehending who you ARE, interpreting sensory data, making decisions! It is a delicate precision instrument that should not be fucked with chemically when one can help its problems organically (say, with cognitive therapy, persistence in behaviors counter to those the illness compels, etc.) Brain drugs most definitely have their place, but they have seeped out of that place in the last 25 years or so. For the sake of general public safety and health, I hope that trend reverses itself. If more folks like this Doc speak up, there is hope for that.