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Malaria resistance gene ups HIV risk
pokkets
follow
7
7-17-2008 2:46 AM
159 views
pokkets
says:
More than two thirds of the world's 33 million people infected with HIV live in sub-Saharan Africa
This variant may help explain why.
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<div style="margin: 12px 0px; font-family: arial; color: #333333; background: #ffffff; border: solid 4px #e5e5e5; width: 100%; clear: left;"><div class="CM_CTB_Content_Wrap" style="margin: 0px; padding: 0px;background-color: #ffffff;"><div style="border-bottom: solid 1px #dcdcdc; white-space: nowrap; margin-bottom: 8px; background-color: #eeeeee ;background-image: url(http://clipmarks.com/images/source-bg.gif); background-repeat: repeat-x; height: 24px; line-height: 24px; vertical-align: middle; padding-bottom: 4px; color: #666666; font-size: 10px;" ><a href="http://clipmarks.com/clip-to-blog/" title="see clips that are hot right now"><img src="http://content.clipmarks.com/blog_embed/e77139a9-d7ba-445e-8439-356cedcd7f49/029955AD-37AB-4600-8C18-29533CEDFEA2/" alt="" width="19" height="19" border="0" style="vertical-align: middle; margin: 0px 4px; display: inline; border: none; float:none;" /></a>clipped from <a title="http://www.abc.net.au/science/articles/2008/07/17/2306625.htm?site=science&topic=latest" href="http://www.abc.net.au/science/articles/2008/07/17/2306625.htm?site=science&topic=latest" style="font-size: 11px;">www.abc.net.au</a></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/07/17/2306625.htm?site=science&topic=latest">Will Dunham</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/07/17/2306625.htm?site=science&topic=latest"><P class="first">A gene variant that emerged thousands of years ago to protect Africans from malaria may raise their vulnerability to HIV infection, but help them live longer once infected, researchers say.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/07/17/2306625.htm?site=science&topic=latest"><div align="center"><img src="http://content9.clipmarks.com/blog_cache/www.abc.net.au/img/BC4826B8-9B04-477E-BA16-9C0C46809114" alt="aids awareness youth" /></div></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/07/17/2306625.htm?site=science&topic=latest"><P>People with the version of the gene have a 40% higher risk of becoming infected with the human immunodeficiency virus (HIV) write US and British researchers in the journal <A target="_blank" href="http://www.cellhostandmicrobe.com/"><EM>Cell Host & Microbe</EM></A>.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/07/17/2306625.htm?site=science&topic=latest">In Africa, the gene variant may account for 11% of HIV infections</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/07/17/2306625.htm?site=science&topic=latest">Sexual behaviour and other social factors cannot completely explain why more than two-thirds of the world's 33 million people infected with HIV live in sub-Saharan Africa</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/07/17/2306625.htm?site=science&topic=latest"> So genes may be playing a pivotal role.</blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/07/17/2306625.htm?site=science&topic=latest"><P>The gene in question controls a protein on the surface of red blood cells.</P></blockquote><div style="height: 2px; font-size: 2px; background: #dcdcdc; border-bottom: solid 1px #f5f5f5; margin: 2px 4px;"></div><blockquote style="text-align: left; padding: 0px 8px; margin: 4px 0px 8px 0px; background: transparent; border: none;" cite="http://www.abc.net.au/science/articles/2008/07/17/2306625.htm?site=science&topic=latest">even as it elevates a person's susceptibility to HIV infection, having this version of the gene seems to slow the progression of AIDS. Those with the variant who have been infected with HIV live roughly two years longer than people who do not have it</blockquote></div><div style="margin: 0px 6px 6px 4px;"><table style="font-size: 11px;border-spacing: 0px;padding: 0px;" cellpadding="0" cellspacing="0" width="100%"><tr><td style="background:transparent;border-width:0px;padding:0px;"> </td><td align="right" style="background:transparent;border-width:0px;padding:0px;width:107px" width="107"><a href="http://clipmarks.com/share/029955AD-37AB-4600-8C18-29533CEDFEA2/blog/" title="blog or email this clip"><img src="http://content6.clipmarks.com/images/c2b-foot.png" border="0" alt="blog it" width="107" height="17" style="border-width:0px;padding:0px;margin:0px;" /></a></td></tr></table></div></div>
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